Member Price: FREE
Available: January 1, 2026
Title: Leucovorin in Autism: An Evidence Based and Clinically Informed Approach
Description:
Advanced practice registered nurses (APRNs) are increasingly caring for children and families seeking treatment options for autism spectrum disorder (ASD), including requests for information regarding folinic acid (leucovorin) as a therapeutic approach for ASD and related neurodevelopmental conditions. However, many APRNs report limited formal education on cerebral folate deficiency, folate receptor alpha autoantibodies, and the evidence-based clinical decision-making required to determine appropriate candidates for treatment. Additionally, there is insufficient understanding of the distinctions between folinic acid and other folate formulations, as well as limited familiarity with ordering and interpreting folate receptor antibody testing and safely dosing or titrating leucovorin. These knowledge gaps contribute to inconsistent clinical evaluation, missed opportunities for early recognition of cerebral folate deficiency, and uncertainty when counseling families regarding treatment considerations.
Presenter: Emily Gutierrez, DNP, APRN, CPNP-PC, PMHS
Release Date: January 1, 2026
Expiration Date: January 1, 2027
Learner Outcome:
At least 80% of learners will demonstrate increased knowledge related to identifying cerebral folate deficiency, interpreting folate-related laboratory testing, and safely evaluating the use of folinic acid therapy in appropriate pediatric patients, as evidenced by achieving a score of 80% or higher on the post-test.
Accreditation:
Learners will be awarded 1 Contact Hour. Completion of the course and evaluation are required.
Provider Statement:
Texas Nurse Practitioners is approved as a provider of nursing continuing professional development by Louisiana State Nurses Association - Approver, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. If you are required to use an activity number or provider number on certificates, please use LSNA Provider N003232
Disclosures:
No disclosures exist for presenters or Nurse Planners of this Educational Activity